Zyflo CR Drug Interactions

Certain medications may cause negative interactions when they are taken with Zyflo CR. Drug interactions with Zyflo CR may occur when the asthma medicine is taken with propranolol, theophylline, or warfarin. Some of these interactions may alter the amount of the medications in your blood. Your healthcare provider may need to monitor the level of the medications in your blood and adjust your dosage as necessary.

An Overview of Zyflo CR Drug Interactions

Zyflo CR™ (zileuton CR) can potentially interact with some other drugs. Some of these medicines that may lead to Zyflo CR interactions include:
 

Zyflo CR Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Zyflo CR is combined with any of the drugs listed above.
 
Propranolol (Inderal, Inderal LA, InnoPran XL)
Taking Zyflo CR with propranolol can increase the level of propranolol in your blood, increasing your risk of side effects. Your healthcare provider should monitor your heart rate and blood pressure and decrease your propranolol dose if necessary.
 
Theophylline (Uniphyl, Theocron, TheoCap, Theo-24, Elixophyllin)
Taking theophylline with Zyflo CR can increase the level of theophylline in your blood, increasing your risk of side effects. Your healthcare provider may need to monitor the level of theophylline in your blood, especially when you are starting or stopping Zyflo CR.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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