Salmeterol is made by GlaxoSmithKline.
How Does Salmeterol Work?
Normally, air moves easily into and out of the lungs through a network of airways. During an
asthma attack, however, the muscles around these airways tighten. This narrows the airways and makes it harder to breathe. This is called bronchospasm.
Salmeterol is part of a class of drugs called beta-adrenergic receptor agonists, or beta agonists for short. Beta agonists stimulate beta receptors in the body, including those on the muscles around airways. This stimulation causes the muscles to relax, which opens up the airways and allows more air to get into and through the lungs. Salmeterol is a long-acting beta agonist. Because it does not work as quickly as short-acting beta agonists, it should not be used for treating an asthma attack. Rather, it is used twice a day in order to prevent attacks.
Salmeterol also has some effects on decreasing the activity of mast cells in the lungs, which play an important role in inflammation and allergic reactions.