Will My Medicines React With Salmeterol?

Monoamine Oxidase Inhibitors (MAOIs)
Salmeterol should be used with extreme caution in combination with MAOIs. Dangerously low blood pressure (hypotension) may result. Talk with your healthcare provider before combining salmeterol with an MAOI.
 
Other Long-Acting Beta Agonists
Salmeterol should not be used in combination with other long-acting beta agonists, as this may increase your risk of a severe asthma attack or even death.
 
Tricyclic Antidepressants
Salmeterol should be used with extreme caution in combination with tricyclic antidepressants. Dangerously low blood pressure (hypotension) or an irregular heart rhythm (arrhythmia) may result. Talk with your healthcare provider before combining salmeterol with a tricyclic antidepressant.
 

Final Thoughts on Drug Interactions With Salmeterol

It is possible that not every salmeterol drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific drug interactions with salmeterol that may apply to you.
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