Several medications can cause negative interactions with Pycnogenol. Drug interactions may occur if it is taken with anticoagulant or antiplatelet medications, blood pressure medications, or diabetes medicines. These interactions could increase your risk of complications, such as bleeding or low blood sugar levels. To avoid Pycnogenol drug interactions, talk to your healthcare provider about all medications you are taking before using the supplement.
Even though it is a "natural" product, Pycnogenol® can potentially interact with a few different medicines. Some of the medicines that may lead to Pycnogenol drug interactions include:
Anticoagulant or antiplatelet medications ("blood thinners"), such as: