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Maxair Drug Interactions
When medications such as beta blockers or tricyclic antidepressants are taken together with Maxair, drug interactions can potentially occur. These drug interactions may make some medicines less effective or cause side effects such as dangerously low blood pressure, low potassium levels, or irregular heart rhythms. Talk with your pharmacist or healthcare provider about any Maxair interactions that may apply to you.
Maxair inhalers will not be made, dispensed, or sold in the United States in their current form after December 31, 2013. Maxair contains chlorofluorocarbons (CFCs), chemicals that deplete the ozone layer. The U.S. Food and Drug Administration (FDA) has set this final date for the medication in order to comply with the Montreal Protocol on Substances That Deplete the Ozone Layer. The manufacturer of Maxair is working on a reformulated, CFC-free version, although it is not yet clear when that product will be available to consumers.
Maxair® (pirbuterol acetate) can potentially interact with a few other medicines. Some of the medicines that may lead to Maxair interactions include:
- Beta blockers, such as:
- Atenolol (Tenormin®)
- Bisoprolol (Zebeta®)
- Metoprolol (Lopressor®, Toprol-XL®)
- Nadolol (Corgard®)
- Propranolol (Inderal®)
- Sotalol (Betapace®)
- Timolol (Blocadren®)
- Carvedilol (Coreg®)
- Labetalol (Trandate®)
- Certain diuretics, such as:
- Bumetanide (Bumex®)
- Chlorothiazide (Diuril®)
- Chlorthalidone (Thalitone®)
- Ethacrynic acid (Edecrin®)
- Furosemide (Lasix®)
- Hydrochlorothiazide (Esidrix®, HydroDIURIL®, Microzide®, Oretic®)
- Metolazone (Zaroxolyn®)
- Torsemide (Demadex®)
- Monoamine oxidase inhibitors (MAOIs), including:
- Isocarboxazid (Marplan®)
- Phenelzine (Nardil®)
- Rasagiline (Azilect®)
- Selegiline (Eldepryl®, Emsam®, Zelapar®)
- Tranylcypromine (Parnate®)
- Tricyclic antidepressants, including:
- Amoxapine (Asendin®)
- Clomipramine (Anafranil®)
- Desipramine (Norpramin®)
- Doxepin (Sinequan®, Silenor®)
- Imipramine (Tofranil®, Tofranil PM®)
- Maprotiline (Ludiomil®)
- Nortriptyline (Pamelor®)
- Protriptyline (Vivactil®)
- Trimipramine (Surmontil®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD