Asthma Home > Zyflo Warnings and Precautions

Some Zyflo warnings and precautions to be aware of include the safety of taking Zyflo while pregnant, the risk of liver damage in some people taking the medication, and people who should not take it at all (such as those who are allergic to Zyflo or any of its components). To reduce the chances of drug interactions, you should tell your healthcare provider (prior to taking Zyflo) about all other drugs you are taking. Among the conditions that you should let your healthcare provider know about prior to treatment with Zyflo are liver disease and any allergies you may have.

In February 2008, the manufacturer of Zyflo announced that it has discontinued making this product. The manufacturer stated that since the longer-acting version, Zyflo CR, became available in 2007, use of immediate-release Zyflo declined significantly. Zyflo CR will still be available.


Zyflo: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Zyflo® (zileuton) if you have:
  • Liver disease, such as liver failure or cirrhosis
  • Any allergies, including allergies to food, dyes, or preservatives.
Also let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also make sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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