Asthma Home > Zyflo and Breastfeeding

In previous animal studies involving Zyflo and breastfeeding, the drug passed through breast milk in rats. However, it is not known whether the medicine passes through breast milk in humans. You should make sure to talk with your healthcare provider about Zyflo and breastfeeding so that the two of you can make a shared decision for you particular situation.

In February 2008, the manufacturer of Zyflo announced that it has discontinued making this product. The manufacturer stated that since the longer-acting version, Zyflo CR, became available in 2007, use of immediate-release Zyflo declined significantly. Zyflo CR will still be available.

An Overview of Zyflo and Breastfeeding

It is not known if Zyflo® (zileuton) passes through breast milk. Because of the potentially serious side effects that could occur in the nursing infant, the manufacturer of Zyflo does not recommend breastfeeding while taking the medication. Therefore, if you are breastfeeding or thinking of breastfeeding and have been prescribed Zyflo, make sure to let your healthcare provider know.

What Does the Research Say About Zyflo and Breastfeeding?

No studies have been conducted on whether Zyflo passes through breast milk in humans. However, it is known that Zyflo passes through breast milk in rats. It is not known if the medicine will cause any negative effects in a breastfed infant. If your healthcare provider recommends taking Zyflo while breastfeeding, be sure to watch for any side effects in your child.

Talking With Your Healthcare Provider About Zyflo and Breastfeeding

You should talk with your healthcare provider about Zyflo and breastfeeding. Everyone's situation is different, and your healthcare provider understands your situation best. After considering what you want and expect (and your current health situation), you and your healthcare provider can make a shared decision about Zyflo and breastfeeding for your particular situation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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