Asthma Home > Drugs That Can Interfere With Proventil HFA
Proventil HFA Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Proventil HFA is combined with any of the drugs listed above.
Taking Proventil HFA and a beta blocker together can decrease the effectiveness of both medications. Additionally, people with asthma should generally avoid beta blockers, as they may worsen their condition. While some beta blockers are less likely than others to interact with Proventil HFA, all beta blockers can potentially cause problems.
Taking Proventil and certain diuretics together can increase your risk of low potassium levels (hypokalemia), especially when you use Proventil more frequently than recommended. Talk to your healthcare provider before using these medications together.
Digoxin (Digitek, Lanoxin)
Proventil HFA may decrease the level of digoxin in your blood, perhaps making it less effective. Your healthcare provider may need to monitor the level of digoxin in your blood and adjust your digoxin dosage as necessary, especially when you are starting or stopping Proventil HFA.
Monoamine Oxidase Inhibitors (MAOIs)
Proventil HFA should be used with extreme caution in combination with MAOIs. Dangerously low blood pressure (hypotension) may result. Talk to your healthcare provider before combining Proventil HFA with an MAOI.
Proventil HFA should be used with extreme caution in combination with tricyclic antidepressants. Dangerously low blood pressure (hypotension) or an irregular heart rhythm (arrhythmia) may result. Talk to your healthcare provider before combining Proventil HFA with a tricyclic antidepressant.