Asthma Home > Specific Drugs That React With Proair HFA
Proair HFA Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Proair HFA is combined with any of the drugs listed above.
Taking Proair HFA and a beta blocker together can decrease the effectiveness of both medications. Additionally, people with asthma should generally avoid beta blockers, as they may make their condition worse. While some beta blockers are less likely than others to interact with Proair HFA, all beta blockers can potentially cause problems.
Taking Proair HFA and certain diuretics together can increase your risk of low potassium levels (hypokalemia), especially when you use Proair HFA more frequently than recommended. Talk with your healthcare provider before using these medications together.
Digoxin (Digitek, Lanoxin)
Proair HFA may decrease the level of digoxin in your blood, perhaps making it less effective. If you are taking these medicines together, your healthcare provider may need to monitor the level of digoxin in your blood and adjust your digoxin dosage as necessary -- especially when you are starting or stopping Proair HFA.
Monoamine Oxidase Inhibitors (MAOIs)
Proair HFA should be used with extreme caution in combination with MAOIs because it may result in dangerously low blood pressure (hypotension). Talk with your healthcare provider before combining Proair HFA with an MAOI.
Proair HFA should be used with extreme caution in combination with tricyclic antidepressants because it may result in dangerously low blood pressure (hypotension) or an irregular heart rhythm (arrhythmia). Talk with your healthcare provider before combining Proair HFA with a tricyclic antidepressant.