Asthma Home > Drug Interactions With Flunisolide Inhalers
Flunisolide inhalers will not be made, dispensed, or sold in the United States after June 30, 2011. Flunisolide inhalers contain chlorofluorocarbons (CFCs), chemicals that deplete the ozone layer. The U.S. Food and Drug Administration (FDA) has set this final date for the medication in order to comply with the Montreal Protocol on Substances That Deplete the Ozone Layer. People using the flunisolide inhaler should ask their healthcare providers about alternatives to the medication, keeping in mind that it is possible that flunisolide inhalers may become unavailable in pharmacies earlier than the final date.
Flunisolide inhalers (Aerobid®) can potentially interact with prednisone (Deltasone®). Combining prednisone with the flunisolide inhaler may increase the risk of side effects. Talk with your healthcare provider before taking these medications together, especially on a regular basis.
Since flunisolide is inhaled directly into the lungs, blood levels of flunisolide are usually low. Medications that would normally interact with flunisolide (if it were taken orally or by injection) are not likely to cause interactions with the flunisolide inhaler, due to the low blood levels of flunisolide. However, people taking a high flunisolide inhaler dosage may have higher levels of flunisolide (and may be more susceptible to drug interactions). Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions with flunisolide inhalers that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Aerobid and Aerobid-M [package insert]. St. Louis, MO: Forest Laboratories, Inc.;2002 March.
Lexi-Interact [computer program]. Lexi-Comp, Inc.; April 24, 2007.
Food and Drug Administration, Center for Drug Evaluation and Research. Asthma and COPD inhalers that contain ozone-depleting CFCs to be phased out; alternative treatments available (4/13/2010). FDA Web site. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm208302.htm. Accessed April 16, 2010.
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