Asthma Home > Advair 45/21

Advair® (fluticasone and salmeterol) is available in a number of strengths. The lowest dosage available in this version of the medication is 45/21, containing 120 inhalations with 45 mcg fluticasone and 21 mcg salmeterol per inhalation. This medication comes in a traditional, metered-dose inhaler, known as the Advair HFA inhaler. The medication is inhaled using the inhaler typically twice a day, with about 12 hours between doses.
The Advair HFA inhaler is only approved for preventing airway spasms in people who have asthma (it is not approved for treating people who have chronic obstructive pulmonary disease, or COPD).
The recommended dose for asthma depends on the dose of other asthma medications taken in the past, varying from two inhalations of 45/21 twice daily to two inhalations of 230/21 twice daily.
(Click Advair Dosage for more information on how the 45/21 strength of Advair can be beneficial in preventing asthma attacks, as well as general dosing guidelines and tips on when and how to use this medication.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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