Safety Concerns With Brethine

Some Brethine Warnings and Precautions

Following are some warnings and precautions to be aware of with Brethine:
  • Brethine can have a stimulatory effect on the heart and blood pressure. A fast heart rate (tachycardia), high blood pressure (hypertension), and irregular heart rhythm (arrhythmia) may occur -- though low blood pressure (hypotension) is also possible. If you have heart disease or high blood pressure, make sure that your healthcare provider is aware of it. He or she may wish to use particular caution if he or she recommends Brethine in your case.
  • People with an overactive thyroid (hyperthyroidism), diabetes, or epilepsy should use caution when taking Brethine, as Brethine may worsen these conditions or increase the risk of side effects.
  • Brethine is not a fast-acting asthma medication and cannot replace fast-acting rescue inhalers. Do not use Brethine to treat an asthma attack. Everyone taking Brethine for asthma should also have a rescue asthma medication available at all times. Let your healthcare provider know if you need to use your rescue inhaler more frequently than usual, as this may be a sign of worsening asthma.
  • Brethine can interact with certain other medications (see Brethine Drug Interactions).
  • Brethine has been used to treat and prevent preterm labor during pregnancy (it is not approved for this use). There are significant risks associated with this use. Talk with your healthcare provider about the risks and benefits of using Brethine during pregnancy (see Terbutaline and Pregnancy and Terbutaline and Preterm Labor for more information).


  • It is not known if Brethine passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about using Brethine (see Terbutaline and Breastfeeding for more information).
ADHD and Girls

Brethine Drug Information

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