Albuterol Inhalers and Pregnancy

In animal studies involving albuterol inhalers and pregnancy, the medicine caused birth defects and brain and skull problems when it was given to pregnant mice and rabbits. Human fetuses exposed to albuterol may be at risk for increased heart rate and blood sugar levels. Despite these possible risks, healthcare providers typically recommend that pregnant women continue to use their albuterol inhalers.

Are Albuterol Inhalers Safe to Use During Pregnancy?

Albuterol inhalers may not be safe for women who are pregnant. In animal studies that looked at the effects of albuterol during pregnancy, the drug caused birth defects.

Albuterol Inhalers and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a Pregnancy Category C rating.
Albuterol inhalers were given a pregnancy Category C rating because of potential problems in animal studies. When given to mice, albuterol caused birth defects, especially cleft palate. In rabbits, albuterol caused brain and skull problems. In humans, albuterol can increase the heart rate and blood sugar levels in the fetus.
However, it is important to note that animals do not always respond to medicines the same way that humans do. A pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child. Because "rescue" medications like albuterol inhalers are usually essential for people with asthma, healthcare providers typically recommend that pregnant women continue to use their albuterol inhalers. Several references state that albuterol inhalers are compatible with pregnancy. In fact, albuterol is sometimes used to treat premature labor, usually without causing any problems in the fetus.
Pregnancy and Pain

Albuterol Asthma Inhaler

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