People who suffer from asthma or chronic obstructive pulmonary disease (COPD) may benefit from using Advair^® (fluticasone and salmeterol), a medication that is available by prescription. The medicine works by opening up the airways to allow more air to get into and through the lungs. Most people tolerate Advair well; and even when side effects occur, they are usually minor. Some side effects of Advair include headaches, a sore throat, and upper respiratory tract infections. If you forget to take your Advair as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double your dose of Advair.