Advair Risks

Although many people do not experience any problems while taking Advair® (fluticasone and salmeterol), this medication is not free of risks. The most important one involves an increased risk of asthma-related deaths in people who take long-acting beta agonists, such as salmeterol, one of the components of Advair.
Individuals whose asthma can be adequately controlled without a long-acting beta agonist should not take this medication, due to the risks. If you must take this medication, once your asthma is under control your healthcare provider should see if you can gradually stop taking this medication (or any other long-acting beta agonist) without causing a worsening of your asthma.
Some of the other more common (but less serious) risks reported with Advair include:
If any problems do occur, they tend to be minor and either require no treatment or are easily treated by you or your healthcare provider. However, there are some potentially serious Advair risks that require immediate medical attention. Contact your healthcare provider if you experience serious problems such as:
  • Breathing problems that are becoming worse
  • An irregular heart rhythm (arrhythmia)
  • High blood sugar
  • Agitation, aggression, anxiety, or restlessness
  • Depression
  • Eye problems, including glaucoma or cataracts
  • A frequent or severe infection of any type
  • Signs of an allergic reaction, including an unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.
Other Advair warnings and precautions apply to women who are pregnant or breastfeeding, as well as people who have certain allergies (including allergies to foods, dyes, or preservatives).
(Click Advair Side Effects and Advair Warnings and Precautions for more information on possible Advair risks, including potentially serious problems that may require immediate medical care.)
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